Description

2-Bromo-5-Fluoropyridine-3,4-Diamine is a high-value, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents adjacent to amine groups, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluoropyridine scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry, cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions), and as a ligand precursor.
• Dye and Pigment Industry: Acts as a starting material for synthesizing complex, color-fast dyes and functional pigments.

Basic Information

Item	Details
Product Name	2-Bromo-5-Fluoropyridine-3,4-Diamine
CAS No.	1227958-29-3
Molecular Formula	C5H5BrFN3
Molecular Weight	206.01 g/mol
Synonyms	3,4-Diamino-2-bromo-5-fluoropyridine; 2-Bromo-5-fluoro-3,4-pyridinediamine; 5-Fluoro-2-bromopyridine-3,4-diamine; 2-Bromo-5-fluoropyridine-3,4-diyldiamine; 1227958-29-3 (CAS Registry)
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-5-Fluoropyridine-3,4-Diamine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.