Description

(2-Bromo-6-Nitrophenethoxy)(tert-Butyl)Dimethylsilane is a high-purity, protected intermediate crucial for advanced organic synthesis. Its value lies in providing a versatile, silyl-protected phenethyl alcohol derivative, enabling complex multi-step reactions with precise regiochemical control. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and specialty chemical production who require reliable building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds with substituted phenethylamine or benzofuran cores.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require bromo- and nitro-substituted aromatic systems.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors, where its protected functionality allows for controlled polymerization or derivatization.
• Cross-Coupling Reactions: The bromo substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological systems and mechanisms.

Basic Information

Product Name	(2-Bromo-6-Nitrophenethoxy)(tert-Butyl)Dimethylsilane
CAS No.	1227958-15-7
Molecular Formula	C14H22BrNO3Si
Molecular Weight	360.33 g/mol
Synonyms	2-Bromo-6-nitrophenethyloxy-tert-butyldimethylsilane; tert-Butyl(2-(2-bromo-6-nitrophenoxy)ethyl)dimethylsilane; 2-(2-Bromo-6-nitrophenoxy)ethyl-tert-butyldimethylsilane; 1-((tert-Butyldimethylsilyl)oxy)-2-(2-bromo-6-nitrophenoxy)ethane; TBDMS ether of 2-(2-bromo-6-nitrophenoxy)ethanol; (2-Bromo-6-nitrophenethoxy)-tert-butyldimethylsilane; Silane, [2-(2-bromo-6-nitrophenoxy)ethoxy](1,1-dimethylethyl)dimethyl-
EINECS	Contact for details

Quality Control

Our (2-Bromo-6-Nitrophenethoxy)(tert-Butyl)Dimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to supply chain integrity and documentation traceability meets the stringent requirements of research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to amber viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.