Description

Methyl 2-Chloro-6-(4-Methylpiperazin-1-Yl)Isonicotinate is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its core value lies in its unique molecular architecture, which combines a chlorinated pyridine core with a methylpiperazine moiety, making it a versatile precursor for the development of novel active compounds. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new drug candidates, particularly in therapeutic areas requiring complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides that leverage its heterocyclic structure for biological activity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and functional materials with specific electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl 2-Chloro-6-(4-Methylpiperazin-1-Yl)Isonicotinate
CAS No.	1227954-55-3
Molecular Formula	C12H16ClN3O2
Molecular Weight	269.73 g/mol
Synonyms	Methyl 2-chloro-6-(4-methyl-1-piperazinyl)isonicotinate; 2-Chloro-6-(4-methylpiperazin-1-yl)isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-chloro-6-(4-methyl-1-piperazinyl)-, methyl ester; Methyl 2-chloro-6-(N-methylpiperazinyl)isonicotinate; 1227954-55-3; Methyl 2-chloro-6-(4-methylpiperazinyl)nicotinate (isomer); 6-(4-Methylpiperazin-1-yl)-2-chloroisonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-6-(4-Methylpiperazin-1-Yl)Isonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports research reproducibility and process development from discovery through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.