Description

(5R,7S)-1-(3-Fluorophenyl)-7-Methyl-1,8-Diazaspiro[4.5]Decan-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and spirocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its defined stereochemistry.
• Preclinical Development: Serves as a critical raw material for producing batches of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying spirocyclic compounds and their biological interactions.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(5R,7S)-1-(3-Fluorophenyl)-7-Methyl-1,8-Diazaspiro[4.5]Decan-2-One
CAS No.	1227685-16-6
Molecular Formula	C16H21FN2O
Molecular Weight	276.35 g/mol
Synonyms	1-(3-Fluorophenyl)-7-methyl-1,8-diazaspiro[4.5]decan-2-one; (5R,7S)-1-(3-Fluorophenyl)-7-methyl-1,8-diazaspiro[4.5]decan-2-one; 1,8-Diazaspiro[4.5]decan-2-one, 1-(3-fluorophenyl)-7-methyl-, (5R,7S)-; UNII-9F8Q8N4V1I; 9F8Q8N4V1I; Spirocyclic Fluorophenyl Diazadecanone; 3-Fluorophenyl Diazaspirodecanone Derivative
EINECS	Contact for details

Quality Control

Our (5R,7S)-1-(3-Fluorophenyl)-7-Methyl-1,8-Diazaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.