Description

2-Chloromethyl-3-Methoxy-6-(Trifluoromethyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and a trifluoromethyl moiety, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its unique electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Chloromethyl-3-Methoxy-6-(Trifluoromethyl)Pyridine
CAS No.	1227606-47-4
Molecular Formula	C8H7ClF3NO
Molecular Weight	225.59 g/mol
Synonyms	2-(Chloromethyl)-3-methoxy-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-methoxy-2-pyridinemethanol, chloromethyl ether; 3-Methoxy-6-trifluoromethyl-2-pyridylmethyl chloride; 2-Pyridinemethanol, 6-(trifluoromethyl)-3-methoxy-, chloromethyl ether; 1227606-47-4
EINECS	Contact for details

Quality Control

Every batch of 2-Chloromethyl-3-Methoxy-6-(Trifluoromethyl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or otherwise light-resistant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.