Description

5-Chloro-3-(Chloromethyl)-2-Fluoropyridine is a high-purity, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of molecular probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-3-(Chloromethyl)-2-Fluoropyridine
CAS No.	1227606-17-8
Molecular Formula	C6H4Cl2FN
Molecular Weight	180.01 g/mol
Synonyms	2-Fluoro-5-chloro-3-(chloromethyl)pyridine; 3-(Chloromethyl)-5-chloro-2-fluoropyridine; 2-Fluoro-3-chloromethyl-5-chloropyridine; 5-Chloro-2-fluoro-3-pyridinylmethyl chloride; 1227606-17-8; 5-Chloro-3-chloromethyl-2-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Chloromethyl)-2-Fluoropyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.