Description

Ethyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate is a high-value, multi-functional chemical intermediate characterized by its nicotinate core and trifluoromethyl substituent. This compound is essential for synthesizing advanced molecules where the introduction of fluorine atoms and specific heterocyclic frameworks is required. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and functional materials that require fluorinated aromatic systems.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and as a ligand or substrate in catalytic reactions.

Basic Information

Product Name	Ethyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate
CAS No.	1227604-63-8
Molecular Formula	C10H10F3NO3
Molecular Weight	249.19 g/mol
Synonyms	Ethyl 2-Methoxy-5-(trifluoromethyl)pyridine-3-carboxylate; 5-(Trifluoromethyl)-2-methoxynicotinic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 2-methoxy-5-(trifluoromethyl)-, ethyl ester; Ethyl 2-methoxy-5-(trifluoromethyl)nicotinate; 1227604-63-8
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.