Description

2-Fluoro-4-formyl-5-chloropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both aldehyde and halogen substituents on the pyridine ring, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-4-formyl-5-chloropyridine
CAS No.	1227603-95-3
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	5-Chloro-2-fluoro-4-pyridinecarboxaldehyde; 5-Chloro-2-fluoropyridine-4-carbaldehyde; 4-Formyl-5-chloro-2-fluoropyridine; 2-Fluoro-5-chloro-4-pyridinecarboxaldehyde; 2-Fluoro-5-chloroisonicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-formyl-5-chloropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA), including purity assay and impurity profile by HPLC, is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.