Description

5-Bromo-6-Chloro-2-Hydroxypyridine is a halogenated pyridine derivative serving as a versatile and critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromo and chloro functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as OLED components and conductive polymers.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	5-Bromo-6-Chloro-2-Hydroxypyridine
CAS No.	1227603-81-7
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	2-Hydroxy-5-bromo-6-chloropyridine; 6-Chloro-5-bromopyridin-2-ol; 5-Bromo-6-chloro-2-pyridinol; 5-Bromo-6-chloro-2(1H)-pyridinone; 2-Pyridinol, 5-bromo-6-chloro-; 5-Bromo-6-chloro-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloro-2-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.