Description

3-Bromo-4-(Bromomethyl)-5-Fluoropyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and materials science.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new heterocyclic chemistry and creating novel molecular libraries for screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.

Basic Information

Product Name	3-Bromo-4-(Bromomethyl)-5-Fluoropyridine
CAS No.	1227603-46-4
Molecular Formula	C6H4Br2FN
Molecular Weight	268.91 g/mol
Synonyms	5-Fluoro-3-bromo-4-(bromomethyl)pyridine; 4-(Bromomethyl)-3-bromo-5-fluoropyridine; 3-Bromo-4-bromomethyl-5-fluoropyridine; 5-Fluoro-3,4-dibromomethylpyridine (incorrect but common search term); Pyridine, 3-bromo-4-(bromomethyl)-5-fluoro-; 1227603-46-4 (CAS-based synonym)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(Bromomethyl)-5-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.