Description

2-Amino-3-Methoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its amino, methoxy, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Key synthetic intermediate for pharmaceutical active ingredients, particularly in kinase inhibitor and CNS drug discovery.
• Building block for the development of agrochemicals, including herbicides and fungicides.
• Precursor in the synthesis of ligands and catalysts for metal-organic chemistry and cross-coupling reactions.
• Research chemical for material science applications, such as in the creation of organic electronic components.
• Intermediate for dye and pigment manufacturing, leveraging its aromatic amine functionality.
• Starting material for fluorinated compound libraries used in medicinal chemistry and screening.

Basic Information

Product Name	2-Amino-3-Methoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227603-09-9
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	5-(Trifluoromethyl)-3-methoxypyridin-2-amine; 3-Methoxy-5-(trifluoromethyl)pyridin-2-amine; 2-Amino-3-methoxy-5-trifluoromethylpyridine; 2-Pyridinamine, 3-methoxy-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-amino-3-methoxypyridine; 2-Amino-3-methoxy-5-(trifluoromethyl)pyridine; 3-Methoxy-5-(trifluoromethyl)-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methoxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.