Description

3-Chloro-4-Iodo-2-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern offers versatile reactivity for constructing complex molecular architectures, making it indispensable for research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of both chloro and iodo substituents, allowing for selective functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Item	Details
Product Name	3-Chloro-4-Iodo-2-Methoxypyridine
CAS No.	1227603-07-7
Molecular Formula	C6H5ClINO
Molecular Weight	269.47 g/mol
Synonyms	2-Methoxy-3-chloro-4-iodopyridine; 4-Iodo-3-chloro-2-methoxypyridine; 3-Chloro-4-iodo-2-pyridinol methyl ether; 3-Chloro-4-iodo-2-methoxy-pyridine; 2-Pyridinol, 3-chloro-4-iodo-, methyl ether
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Iodo-2-Methoxypyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.