Description

2,5-Difluoro-4-(Hydroxymethyl)Pyridine is a high-value, multi-functional pyridine derivative characterized by its difluoro substitution and hydroxymethyl group. This unique structure makes it a critical pharmaceutical intermediate and versatile building block for advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the creation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Fluorinated Compound Library: Essential for medicinal chemistry research in constructing diverse fluorinated compound libraries for drug discovery screening.
• Custom Synthesis: Starting material for the contract synthesis of complex, fluorinated organic molecules.

Basic Information

Product Name	2,5-Difluoro-4-(Hydroxymethyl)Pyridine
CAS No.	1227601-53-7
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	4-(Hydroxymethyl)-2,5-difluoropyridine; 2,5-Difluoropyridine-4-methanol; 2,5-Difluoro-4-pyridinemethanol; (2,5-Difluoropyridin-4-yl)methanol; 4-Pyridinemethanol, 2,5-difluoro-; Difluorohydroxymethylpyridine; DFHMP
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-(Hydroxymethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.