Description

4-Bromo-3-Fluoro-2-Methoxypyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical research and development teams, agrochemical manufacturers, and specialty chemical companies engaged in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for creating organic electronic materials, such as components for OLEDs or conductive polymers, where the methoxy and halogen groups fine-tune electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Methoxypyridine
CAS No.	1227599-41-8
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Methoxy-4-bromo-3-fluoropyridine; 3-Fluoro-4-bromo-2-methoxypyridine; 4-Bromo-3-fluoro-2-methoxypyridine; 2-Methoxy-3-fluoro-4-bromopyridine; Pyridine, 4-bromo-3-fluoro-2-methoxy-; 1227599-41-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.