Description

Pyridine, 6-Chloro-2-Fluoro-3-Methyl- is a high-purity, multi-substituted pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized heterocyclic compounds for advanced materials, including organic semiconductors and liquid crystals.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and protein-ligand interactions.
• Custom Synthesis and Contract Manufacturing: A vital intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Pyridine, 6-Chloro-2-Fluoro-3-Methyl-
CAS No.	1227598-47-1
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	6-Chloro-2-fluoro-3-methylpyridine; 3-Methyl-6-chloro-2-fluoropyridine; 2-Fluoro-6-chloro-3-methylpyridine; 6-Chloro-2-fluoro-3-picoline; 2-Fluoro-3-methyl-6-chloropyridine; 6-Chloro-2-fluoro-3-methyl-pyridine; 3-Methyl-2-fluoro-6-chloropyridine; 2-Fluoro-6-chloro-3-methyl-pyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 6-Chloro-2-Fluoro-3-Methyl- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the rigorous standards required for pharmaceutical and agrochemical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.