Description

4-Bromo-6-Fluoro-2(1H)-Pyridinone is a halogenated pyridinone derivative, a versatile and high-value heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridinone core.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and functionalized polymers.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to introduce complex aryl/heteroaryl groups.
• Library Synthesis for Drug Discovery: A valuable building block for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	4-Bromo-6-Fluoro-2(1H)-Pyridinone
CAS No.	1227597-80-9
Molecular Formula	C5H2BrFNO
Molecular Weight	191.98 g/mol
Synonyms	4-Bromo-6-fluoropyridin-2(1H)-one; 6-Fluoro-4-bromo-2(1H)-pyridinone; 2-Hydroxy-4-bromo-6-fluoropyridine; 4-Bromo-6-fluoro-1H-pyridin-2-one; 4-Bromo-6-fluoro-2-hydroxypyridine; 4-Bromo-6-fluoro-2-pyridinol
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-Fluoro-2(1H)-Pyridinone is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.