Description

5-Iodo-6-(Trifluoromethyl)Pyridin-2-Amine CAS NO 1227596-12-4 is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is prized for its unique molecular architecture, which combines an iodine substituent and a trifluoromethyl group on a pyridine-2-amine scaffold, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging the bioactivity of the halogenated pyridine core.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution, facilitating complex molecule construction.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Iodo-6-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1227596-12-4
Molecular Formula	C6H4F3IN2
Molecular Weight	288.01 g/mol
Synonyms	2-Amino-5-iodo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-5-iodopyridin-2-amine; 5-Iodo-6-trifluoromethylpyridin-2-amine; 1227596-12-4; 5-Iodo-6-(trifluoromethyl)-2-pyridinamine; 2-Pyridinamine, 5-iodo-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Iodo-6-(Trifluoromethyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.