Description

2-Chloro-6-Phenylpyridine-3-Carboxaldehyde is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an aldehyde group and a halogenated pyridine ring, which makes it an essential precursor for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with tailored activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific functionalized pyridine derivatives.

Basic Information

Product Name	2-Chloro-6-Phenylpyridine-3-Carboxaldehyde
CAS No.	1227596-08-8
Molecular Formula	C₁₂H₈ClNO
Molecular Weight	217.65 g/mol
Synonyms	2-Chloro-6-phenyl-3-pyridinecarboxaldehyde; 3-Formyl-2-chloro-6-phenylpyridine; 6-Phenyl-2-chloropyridine-3-carbaldehyde; 2-Chloro-6-phenylnicotinaldehyde; 2-Chloro-6-phenyl-3-formylpyridine; 1227596-08-8; 2-Chloro-6-phenyl-pyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Phenylpyridine-3-Carboxaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with comprehensive identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. We support compliance with global regulatory frameworks, including REACH and TSCA.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.