Description

5-Chloro-6-Trifluoromethyl-Pyridin-2-Ylamine is a high-value pyridine derivative and a key fluorinated aromatic amine building block. This compound is essential for the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes and enzyme inhibitors in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	5-Chloro-6-Trifluoromethyl-Pyridin-2-Ylamine
CAS No.	1227595-72-3
Molecular Formula	C7H4ClF3N2
Molecular Weight	208.57 g/mol
Synonyms	2-Amino-5-chloro-6-(trifluoromethyl)pyridine; 5-Chloro-6-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 5-chloro-6-(trifluoromethyl)-; 5-Chloro-6-trifluoromethyl-2-aminopyridine; 5-Chloro-6-trifluoromethyl-pyridin-2-ylamine; 1227595-72-3; CTPYA
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Trifluoromethyl-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.