Description

4-Chloro-3-Methylpyridin-2-Amine is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular construction. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways in academic and industrial R&D.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	4-Chloro-3-Methylpyridin-2-Amine
CAS No.	1227595-52-9
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	2-Amino-4-chloro-3-methylpyridine; 3-Methyl-4-chloropyridin-2-amine; 4-Chloro-3-methyl-2-pyridinamine; 4-Chloro-3-methyl-2-aminopyridine; 2-Pyridinamine, 4-chloro-3-methyl-; 4-Chloro-3-methylpyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methylpyridin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of our global clientele in regulated industries. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.