Description

6-Amino-2-Trifluoromethyl-Nicotinic Acid Methyl Ester is a high-value pharmaceutical intermediate and versatile building block in organic synthesis. Its molecular structure, featuring both an amino group and a trifluoromethyl substituent on a nicotinic acid ester core, makes it a critical precursor for the development of novel active compounds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds and functionalized pyridine derivatives in medicinal chemistry.
• Material Science: Potential monomer or additive for creating advanced polymers and functional materials with specific electronic or surface properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library development for high-throughput screening.

Basic Information

Product Name	6-Amino-2-Trifluoromethyl-Nicotinic Acid Methyl Ester
CAS No.	1227594-94-6
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	Methyl 6-Amino-2-(trifluoromethyl)nicotinate; 2-(Trifluoromethyl)-6-aminonicotinic Acid Methyl Ester; 6-Amino-2-trifluoromethyl-pyridine-3-carboxylic Acid Methyl Ester; 3-Pyridinecarboxylic Acid, 6-Amino-2-(trifluoromethyl)-, Methyl Ester; Methyl 6-Amino-2-(trifluoromethyl)-3-pyridinecarboxylate; 6-Amino-2-(trifluoromethyl)nicotinic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 6-Amino-2-Trifluoromethyl-Nicotinic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.