Description

3-Bromo-2-Hydroxy-4-(Trifluoromethyl)Pyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, a hydroxyl group, and a trifluoromethyl substituent, makes it an exceptionally versatile intermediate for introducing complexity and specific functionality into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its halogen and fluorine content.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-Hydroxy-4-(Trifluoromethyl)Pyridine
CAS No.	1227591-86-7
Molecular Formula	C7H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-Hydroxy-3-bromo-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-bromo-2-pyridinol; 3-Bromo-4-(trifluoromethyl)pyridin-2-ol; 3-Bromo-2-pyridinol, 4-(trifluoromethyl)-; 2-Pyridinol, 3-bromo-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your stringent R&D and scale-up requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.