Description

2-Chloromethyl-3-Fluoro-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring reactive chloromethyl and electron-withdrawing trifluoromethyl groups, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and fluorine motifs.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical companies offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-Chloromethyl-3-Fluoro-6-(Trifluoromethyl)Pyridine
CAS No.	1227590-95-5
Molecular Formula	C8H4ClF4N
Molecular Weight	225.57 g/mol
Synonyms	3-Fluoro-6-(trifluoromethyl)-2-pyridinemethanol, chloride; 2-(Chloromethyl)-3-fluoro-6-(trifluoromethyl)pyridine; 2-Pyridinemethanol, 3-fluoro-6-(trifluoromethyl)-, chloride; 3-Fluoro-2-chloromethyl-6-trifluoromethylpyridine; 6-(Trifluoromethyl)-3-fluoro-2-pyridylmethyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloromethyl-3-Fluoro-6-(Trifluoromethyl)Pyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.