Description

2-Chloro-4-Chloromethyl-5-Fluoro-Pyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring reactive chloro and chloromethyl groups on a fluorinated pyridine ring, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-4-Chloromethyl-5-Fluoro-Pyridine
CAS No.	1227585-30-9
Molecular Formula	C7H4Cl2FN
Molecular Weight	180.02 g/mol
Synonyms	5-Fluoro-2-chloro-4-(chloromethyl)pyridine; 4-(Chloromethyl)-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-4-pyridinylmethyl chloride; 2-Chloro-5-fluoro-4-(chloromethyl)pyridine; 1227585-30-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Chloromethyl-5-Fluoro-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.