Description

3-Methoxy-6-(Trifluoromethyl)Pyridine-2-Carbaldehyde is a high-purity, multi-functional heterocyclic aldehyde building block. This compound is valued for its unique trifluoromethyl and methoxy substituents, which impart specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by R&D and process development chemists in the pharmaceutical and agrochemical industries for constructing complex active ingredients. Its role as a key intermediate enables the development of novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Methoxy-6-(Trifluoromethyl)Pyridine-2-Carbaldehyde
CAS No.	1227584-28-2
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-Formyl-3-methoxy-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-methoxypyridine-2-carboxaldehyde; 3-Methoxy-6-trifluoromethyl-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 3-methoxy-6-(trifluoromethyl)-; 3-Methoxy-6-(trifluoromethyl)picolinaldehyde
EINECS	Contact for details

Quality Control

Our production of 3-Methoxy-6-(Trifluoromethyl)Pyridine-2-Carbaldehyde adheres to stringent quality management protocols. Every batch is analytically verified using HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.