Description

5-Bromo-6-Chloropicolinaldehyde is a versatile and high-purity halogenated picolinaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure makes it an indispensable intermediate for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-6-Chloropicolinaldehyde
CAS No.	1227583-91-6
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Chloro-5-bromopicolinaldehyde; 5-Bromo-6-chloro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 5-bromo-6-chloro-; 5-Bromo-6-chloropyridine-2-carbaldehyde; 5-Bromo-6-chloro-2-formylpyridine; 2-Formyl-5-bromo-6-chloropyridine; 5-Br-6-Cl-picolinaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.