Description

2-Amino-4-Fluoro-3-(Trifluoromethyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both amino and trifluoromethyl groups, makes it an essential intermediate for creating complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Serves as a precursor for nitrogen-containing ligands used in catalysis and material science.
• Fluorinated Compound Research: Essential for studying the effects of fluorine substitution on molecular properties in medicinal and materials chemistry.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Amino-4-Fluoro-3-(Trifluoromethyl)Pyridine
CAS No.	1227581-71-6
Molecular Formula	C6H4F4N2
Molecular Weight	180.11 g/mol
Synonyms	2-Amino-4-fluoro-3-(trifluoromethyl)pyridine; 4-Fluoro-3-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 4-fluoro-3-(trifluoromethyl)-; 1227581-71-6; 4-Fluoro-3-trifluoromethyl-pyridin-2-ylamine; 2-Amino-4-fluoro-3-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Fluoro-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.