Description

(5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Methanol is a high-value trifluoromethylpyridine derivative, a critical building block in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which combines a trifluoromethyl group for enhanced lipophilicity and metabolic stability with a hydroxymethyl handle for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for candidates targeting CNS disorders and advanced crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) therapeutics and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Building Block: A versatile starting material for introducing the trifluoromethylpyridine moiety into more complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific R&D and scale-up projects.

Basic Information

Product Name	(5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Methanol
CAS No.	1227581-36-3
Molecular Formula	C8H8F3NO2
Molecular Weight	207.15 g/mol
Synonyms	3-(Hydroxymethyl)-2-methoxy-5-(trifluoromethyl)pyridine; 2-Methoxy-5-(trifluoromethyl)pyridin-3-ylmethanol; (2-Methoxy-5-(trifluoromethyl)pyridin-3-yl)methanol; 5-(Trifluoromethyl)-2-methoxynicotinyl alcohol; 3-Pyridinemethanol, 2-methoxy-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (5-(Trifluoromethyl)-2-Methoxypyridin-3-Yl)Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.