Description

2-Fluoro-6-Methylpyridin-4-Ol is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and hydroxyl substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing fluorine group.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Fluoro-6-Methylpyridin-4-Ol
CAS No.	1227577-13-0
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	4-Hydroxy-2-fluoro-6-methylpyridine; 2-Fluoro-6-methyl-4-pyridinol; 2-Fluoro-6-methyl-4-hydroxypyridine; 6-Methyl-2-fluoropyridin-4-ol; 4-Pyridinol, 2-fluoro-6-methyl-; 2-Fluoro-6-methyl-4(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Methylpyridin-4-Ol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.