Description

3-Fluoro-2-Bromo-4-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine, bromine, and trifluoromethyl substituents, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine and trifluoromethyl groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and electronic materials requiring specific halogenated motifs.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-Fluoro-2-Bromo-4-(Trifluoromethyl)Pyridine
CAS No.	1227577-05-0
Molecular Formula	C6H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	2-Bromo-3-fluoro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-fluoro-2-bromopyridine; 3-Fluoro-2-bromo-4-trifluoromethylpyridine; Pyridine, 2-bromo-3-fluoro-4-(trifluoromethyl)-; 1227577-05-0; 2-Bromo-3-fluoro-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Bromo-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades Available)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.