Description

5-Fluoro-2-Hydroxy-4-Iodopyridine is a high-value, multi-functional halogenated pyridine derivative. This compound serves as a critical building block in advanced organic synthesis, prized for its unique reactivity profile that allows for selective functionalization. It is primarily utilized by pharmaceutical R&D and agrochemical scientists for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated and iodinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated heterocycles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals due to its halogen-substituted aromatic core.
• Chemical Biology Probe: Useful for synthesizing molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital substrate for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	5-Fluoro-2-Hydroxy-4-Iodopyridine
CAS No.	1227576-86-4
Molecular Formula	C5H3FINO
Molecular Weight	238.99 g/mol
Synonyms	4-Iodo-5-fluoro-2-hydroxypyridine; 5-Fluoro-4-iodopyridin-2-ol; 2-Hydroxy-5-fluoro-4-iodopyridine; 4-Iodo-5-fluoropyridin-2-ol; 5-Fluoro-4-iodo-2-pyridinol; 2-Pyridinol, 5-fluoro-4-iodo-; 5-Fluoro-4-iodo-2(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxy-4-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.