Description

Methyl 2-Bromo-5-Methylpyridine-4-Carboxylate is a high-purity, versatile brominated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen handle and a protected carboxylic acid group, enabling efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for candidates targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with pyridine-based active cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	Methyl 2-Bromo-5-Methylpyridine-4-Carboxylate
CAS No.	1227575-00-9
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-5-methylisonicotinic acid methyl ester; Methyl 2-bromo-5-methylisonicotinate; 4-Pyridinecarboxylic acid, 2-bromo-5-methyl-, methyl ester; 2-Bromo-5-methyl-4-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-5-Methylpyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.