Description

2,3-Dihydroxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and dihydroxy substitution pattern. This compound is critical for researchers and manufacturers seeking to incorporate fluorine atoms and chelating hydroxyl groups into advanced molecular architectures. It is primarily utilized in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials. Its specific structure makes it a versatile intermediate for developing compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand & Chelating Agent: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs) due to its adjacent hydroxyl groups.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Research & Development: A valuable building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	2,3-Dihydroxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227574-71-1
Molecular Formula	C6H4F3NO2
Molecular Weight	179.10 g/mol
Synonyms	5-(Trifluoromethyl)pyridine-2,3-diol; 2,3-Dihydroxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2,3-dihydroxypyridine; 2,3-Dihydroxy-5-trifluoromethylpyridine; 5-Trifluoromethyl-2,3-dihydroxypyridine; 2,3-Pyridinediol, 5-(trifluoromethyl)-; 2,3-Dihydroxy-5-(trifluoromethyl)pyridine (CAS 1227574-71-1)
EINECS	Contact for details

Quality Control

Our 2,3-Dihydroxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.