Description

4-Iodo-5-Methylpyridin-2(1H)-One is a high-value halogenated pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine atom and a lactam moiety, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the iodine atom can be leveraged for further functionalization or as a leaving group in cross-coupling reactions.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the pyridinone scaffold into more complex molecular architectures.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for contract research organizations (CROs) supporting drug discovery projects.

Basic Information

Product Name	4-Iodo-5-Methylpyridin-2(1H)-One
CAS No.	1227570-92-4
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	4-Iodo-5-methyl-1H-pyridin-2-one; 4-Iodo-5-methyl-2(1H)-pyridinone; 5-Methyl-4-iodopyridin-2(1H)-one; 2-Hydroxy-4-iodo-5-methylpyridine; 4-Iodo-5-methyl-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Iodo-5-Methylpyridin-2(1H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.