Description

4-Bromo-2-Fluoro-6-Methylpyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, where the bromine and fluorine substituents offer orthogonal sites for selective cross-coupling and functionalization reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic cores found in drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological mechanisms and interactions.
• Custom Synthesis and Scale-up: Provides a versatile starting point for contract research organizations (CROs) and CDMOs for custom synthesis projects.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Methylpyridine
CAS No.	1227565-50-5
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Fluoro-4-bromo-6-methylpyridine; 6-Methyl-4-bromo-2-fluoropyridine; 4-Bromo-2-fluoro-6-picoline; Pyridine, 4-bromo-2-fluoro-6-methyl-; 1227565-50-5
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-6-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.