Description

2-Chloro-6-Fluoronicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique halogenated structure makes it an indispensable precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6-Fluoronicotinaldehyde
CAS No.	1227563-22-5
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	6-Fluoro-2-chloropyridine-3-carboxaldehyde; 3-Formyl-2-chloro-6-fluoropyridine; 2-Chloro-6-fluoropyridine-3-carbaldehyde; 2-Chloro-6-fluoro-3-pyridinecarboxaldehyde; 2-Chloro-6-fluoro-3-formylpyridine; 2-Chloro-6-fluoronicotinaldehyde; 1227563-22-5; 6-Fluoro-2-chloronicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluoronicotinaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.