Description

4-Pyridinecarboxaldehyde, 5-Bromo-1,2-Dihydro-2-Oxo- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and functional materials, where its unique brominated and oxidized pyridine structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the global fine chemical market.

Basic Information

Product Name	4-Pyridinecarboxaldehyde, 5-Bromo-1,2-Dihydro-2-Oxo-
CAS No.	1227562-37-9
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	5-Bromo-2-oxo-1,2-dihydropyridine-4-carbaldehyde; 5-Bromo-4-formyl-2(1H)-pyridinone; 5-Bromo-2-hydroxypyridine-4-carboxaldehyde (tautomer); 5-Bromo-4-pyridinecarboxaldehyde-2(1H)-one; 5-Bromo-1,2-dihydro-2-oxo-4-pyridinecarboxaldehyde; 4-Formyl-5-bromo-2-pyridone; 5-Bromo-2-pyridone-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxaldehyde, 5-Bromo-1,2-Dihydro-2-Oxo- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.