Description

Pyridine, 3-(Bromomethyl)-2-Chloro-6-Fluoro- is a multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromomethyl, chloro, and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key functional groups and modulate the biological activity of target compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require halogenated pyridine cores.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized organic materials and liquid crystals.
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and fine chemical manufacturers for bespoke synthesis projects.

Basic Information

Product Name	Pyridine, 3-(Bromomethyl)-2-Chloro-6-Fluoro-
CAS No.	1227516-84-8
Molecular Formula	C7H6BrClFN
Molecular Weight	238.48 g/mol
Synonyms	2-Chloro-6-fluoro-3-(bromomethyl)pyridine; 3-(Bromomethyl)-2-chloro-6-fluoropyridine; 2-Chloro-3-(bromomethyl)-6-fluoropyridine; 6-Fluoro-2-chloro-3-(bromomethyl)pyridine; (2-Chloro-6-fluoropyridin-3-yl)methyl bromide; Pyridine, 2-chloro-6-fluoro-3-(bromomethyl)-; Bromomethyl-chloro-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 3-(Bromomethyl)-2-Chloro-6-Fluoro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.