Description

2-Amino-4-Iodo-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block. This compound is specifically engineered for advanced synthesis, offering a unique combination of a reactive amino group, a versatile halogen substituent, and a stable trifluoromethyl moiety. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and target engagement.
• Fluorinated Compound Libraries: An essential building block for constructing diverse compound libraries in medicinal chemistry for high-throughput screening.
• Advanced Material Development: Used in the research of organic electronic materials and liquid crystals due to its specific electronic properties.

Basic Information

Product Name	2-Amino-4-Iodo-5-(Trifluoromethyl)Pyridine
CAS No.	1227515-42-5
Molecular Formula	C6H4F3IN2
Molecular Weight	288.01 g/mol
Synonyms	5-(Trifluoromethyl)-4-iodopyridin-2-amine; 4-Iodo-5-(trifluoromethyl)pyridin-2-amine; 2-Amino-4-iodo-5-trifluoromethylpyridine; 4-Iodo-2-amino-5-(trifluoromethyl)pyridine; 2-Pyridinamine, 4-iodo-5-(trifluoromethyl)-; 1227515-42-5
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Iodo-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.