Description

5-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a trifluoromethyl group on the pyridine core, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials due to its halogenated and fluorinated characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol
CAS No.	1227515-14-1
Molecular Formula	C6H3F3INO
Molecular Weight	288.99 g/mol
Synonyms	2-Hydroxy-5-iodo-6-(trifluoromethyl)pyridine; 5-Iodo-6-(trifluoromethyl)-2-pyridinol; 5-Iodo-6-(trifluoromethyl)-2(1H)-pyridinone; 5-Iodo-6-(trifluoromethyl)pyridin-2(1H)-one; 6-(Trifluoromethyl)-5-iodopyridin-2-ol
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Production of 5-Iodo-6-(Trifluoromethyl)Pyridin-2-Ol is supported by comprehensive analytical control, including HPLC, GC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our facility operates under cGMP principles where applicable, ensuring traceability and documentation for regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.