Description

3-Bromo-2,4-difluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for introducing specific reactivity and physicochemical properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated pyridine cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Material Science: Building block for creating functionalized ligands in catalysis and for synthesizing advanced organic electronic materials.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine atom.
• Fluorine Chemistry Research: An important reagent for studying the effects of fluorine substitution on aromatic systems and for developing new fluorination methodologies.
• Liquid Crystal & OLED Materials: Intermediate in the production of specialty chemicals for display and lighting technologies.

Basic Information

Product Name	3-Bromo-2,4-difluoropyridine
CAS No.	1227502-60-4
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	2,4-Difluoro-3-bromopyridine; 3-Bromo-2,4-difluoropyridine; Pyridine, 3-bromo-2,4-difluoro-; 3-Br-2,4-F2Py
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,4-difluoropyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are designed to meet the exacting requirements of research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.