Description

(2-Bromo-5-Fluoropyridin-4-Yl)Methanol CAS NO 1227502-29-5 is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites—the bromine and the hydroxymethyl group—which enable precise molecular construction and diversification. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals and organic semiconductors.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags to study biological systems.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific, multi-functionalized heterocycles.

Basic Information

Product Name	(2-Bromo-5-Fluoropyridin-4-Yl)Methanol
CAS No.	1227502-29-5
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	4-(Hydroxymethyl)-2-bromo-5-fluoropyridine; 2-Bromo-5-fluoro-4-pyridinemethanol; (2-Bromo-5-fluoro-4-pyridinyl)methanol; 2-Bromo-5-fluoro-4-(hydroxymethyl)pyridine; 5-Fluoro-2-bromo-4-pyridinemethanol; 4-Pyridinemethanol, 2-bromo-5-fluoro-
EINECS	Contact for details

Quality Control

Our (2-Bromo-5-Fluoropyridin-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.