Description

2-Fluoro-3-Chloro-4-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring fluorine, chlorine, and trifluoromethyl substituents, is engineered to impart specific electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve biological activity and environmental profile.
• Material Science Precursor: Serves as a building block for specialty chemicals, liquid crystals, and advanced polymers requiring specific halogenated aromatic components.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, catalysis, and the synthesis of complex heterocyclic compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-3-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	1227496-80-1
Molecular Formula	C7H2ClF4N
Molecular Weight	199.54 g/mol
Synonyms	2-Fluoro-3-chloro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-fluoro-3-chloropyridine; 3-Chloro-2-fluoro-4-(trifluoromethyl)pyridine; Pyridine, 2-fluoro-3-chloro-4-(trifluoromethyl)-; 2-F-3-Cl-4-CF3-Pyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated pyridine intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.