Description

3-Bromo-2-Chloro-6-(Chloromethyl)Pyridine is a high-purity halogenated pyridine derivative, a crucial advanced intermediate in modern organic synthesis. Its multi-functional halogenated structure makes it a versatile and valuable building block for constructing complex molecules with precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the pyridine core is a common bioactive scaffold.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals or organic semiconductors, due to its modifiable halogen handles.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-Chloro-6-(Chloromethyl)Pyridine
CAS No.	1227496-11-8
Molecular Formula	C6H4BrCl2N
Molecular Weight	240.91 g/mol
Synonyms	2-Chloro-3-bromo-6-(chloromethyl)pyridine; 6-(Chloromethyl)-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-6-chloromethylpyridine; Pyridine, 3-bromo-2-chloro-6-(chloromethyl)-; (3-Bromo-2-chloropyridin-6-yl)methyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-6-(Chloromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets your specified requirements. We support cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.