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5-Bromo-3-(Chloromethyl)Pyridin-2-Amine CAS NO 1227493-85-7


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CAS No.:1227493-85-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-3-(Chloromethyl)Pyridin-2-Amine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals, where precise molecular architecture is critical.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
  • Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic libraries for screening and discovery.
  • Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
  • Material Science: A potential monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.

Basic Information

Product Name 5-Bromo-3-(Chloromethyl)Pyridin-2-Amine
CAS No. 1227493-85-7
Molecular Formula C6H6BrClN2
Molecular Weight 221.48 g/mol
Synonyms 2-Amino-5-bromo-3-(chloromethyl)pyridine; 5-Bromo-3-(chloromethyl)-2-pyridinamine; 2-Pyridinamine, 5-bromo-3-(chloromethyl)-; 3-(Chloromethyl)-5-bromopyridin-2-amine
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Quality Control

Our 5-Bromo-3-(Chloromethyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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