Description

(1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanol (Saltdata: 2HCl) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1227465-76-0. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for the research and development of new APIs with potential therapeutic applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and safety profiles.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study specific biological pathways and protein interactions.

Basic Information

Product Name	(1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanol (Saltdata: 2HCl)
CAS No.	1227465-76-0
Molecular Formula	C9H15N3O · 2HCl
Molecular Weight	266.16 g/mol (as free base: 181.24 g/mol)
Synonyms	1-Methyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridin-3-ylmethanol dihydrochloride; 3-(Hydroxymethyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride; 1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-methanol hydrochloride (1:2); (1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanol dihydrochloride; 1227465-76-0 (CAS); Pyrazolopyridine methanol derivative HCl salt.
EINECS	Contact for details

Quality Control

Our (1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanol dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent specifications suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.