Description

1,3-Dioxa-8-Azaspiro[4.5]Decan-2-One (Saltdata: HCl) is a high-purity, specialized heterocyclic building block and pharmaceutical intermediate. This compound is valued for its unique spirocyclic structure, which is critical for imparting specific conformational and pharmacokinetic properties in advanced drug molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic scaffold for bioactivity.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating new heterocyclic compounds and molecular libraries.
• Ligand and Catalyst Development: Utilized in the design of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with specific chemical properties.

Basic Information

Product Name	1,3-Dioxa-8-Azaspiro[4.5]Decan-2-One (Saltdata: HCl)
CAS No.	1227465-63-5
Molecular Formula	C8H13NO3 • HCl
Molecular Weight	207.65 g/mol (HCl salt)
Synonyms	8-Aza-1,3-dioxaspiro[4.5]decan-2-one hydrochloride; 1,3-Dioxa-8-azaspiro[4.5]decan-2-one hydrochloride; Spiro[1,3-dioxolane-2,4'-piperidine]-2-one hydrochloride; 2-Oxo-1,3-dioxa-8-azaspiro[4.5]decane hydrochloride; 8-Azaspiro[4.5]decane-1,3-dioxol-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our 1,3-Dioxa-8-Azaspiro[4.5]Decan-2-One (Saltdata: HCl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.