Description

Benzyl 2,7-Diazaspiro[3.5]Nonane-2-Carboxylate is a high-value, spirocyclic organic building block of significant interest in advanced pharmaceutical research and development. Its unique diazaspiro[3.5]nonane scaffold provides a rigid, three-dimensional framework that is crucial for modulating the biological activity and physicochemical properties of novel drug candidates. This compound is primarily sought after by medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Scaffold: Used to introduce conformational constraint into drug-like molecules, improving potency, selectivity, and metabolic stability.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the design of bifunctional PROTAC molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized spirocyclic chemistry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic methodology and novel heterocycle research.

Basic Information

Product Name	Benzyl 2,7-Diazaspiro[3.5]Nonane-2-Carboxylate
CAS No.	1227456-92-9
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	Benzyl 2,7-Diazaspiro[3.5]nonane-2-carboxylate; 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid benzyl ester; 2-Benzyloxycarbonyl-2,7-diazaspiro[3.5]nonane; 2-Cbz-2,7-diazaspiro[3.5]nonane; 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, phenylmethyl ester; Benzyl 2-azaspiro[3.5]nonane-2-carboxylate (related core); 7-Benzyl 2,7-diazaspiro[3.5]nonane-2-carboxylate
EINECS	Contact for details

Quality Control

Our Benzyl 2,7-Diazaspiro[3.5]Nonane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.