Description

2-Bromo-5-(Ethylsulfonyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and an ethylsulfonyl group on the pyridine ring, enabling precise cross-coupling reactions and serving as a key synthon for molecular diversification. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its sulfonyl and halogen functionalities.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-Bromo-5-(Ethylsulfonyl)Pyridine
CAS No.	1227384-81-7
Molecular Formula	C7H8BrNO2S
Molecular Weight	250.11 g/mol
Synonyms	5-(Ethylsulfonyl)-2-bromopyridine; 2-Bromo-5-ethylsulfonylpyridine; Pyridine, 2-bromo-5-(ethylsulfonyl)-; 2-Bromo-5-(ethylsulfonyl)pyridine; 2-Bromo-5-(ethanesulfonyl)pyridine; 1227384-81-7; 2-Br-5-EtSO2-Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Ethylsulfonyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development under ISO guided standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.