Description

tert-Butyl 3-((3-Bromopyridin-2-yl)oxy)azetidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-pyrindine hybrid scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by pharmaceutical companies and research institutions engaged in the synthesis of new drug candidates, particularly in areas targeting neurological disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The bromopyridinyl-oxazetidine structure is valuable for creating potential kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 3-((3-Bromopyridin-2-yl)oxy)azetidine-1-carboxylate
CAS No.	1227381-94-3
Molecular Formula	C13H17BrN2O3
Molecular Weight	329.19 g/mol
Synonyms	1-Boc-3-((3-bromopyridin-2-yl)oxy)azetidine; 3-((3-Bromo-2-pyridinyl)oxy)-1-[(1,1-dimethylethoxy)carbonyl]azetidine; tert-Butyl 3-[(3-bromopyridin-2-yl)oxy]azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-((3-bromopyridin-2-yl)oxy)azetidine; Azetidine, 3-((3-bromo-2-pyridinyl)oxy)-1-[(1,1-dimethylethoxy)carbonyl]-; BOC-3-(3-Bromopyridin-2-yloxy)azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-((3-Bromopyridin-2-yl)oxy)azetidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.